Role Of Vincristine In Treatment Of Refractory Idiopathic Thrombocytopenic Purpura (Itp)
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منابع مشابه
Role Of Vincristine In Treatment Of Refractory Idiopathic Thrombocytopenic Purpura (Itp)
Chronic immune thrombocytopenia (ITP) is a condition associated with significant morbidity; however the management options for refractory ITP are often unsatisfactory despite various lines of treatment including splenectomy. The comparison of vincristine costs with other lines of treatment as intravenous immunoglobulin revealed many folds lower costs of vincristine. The aims of this study are: ...
متن کاملAbout treatment of idiopathic thrombocytopenic purpura (ITP).
Their treatment results with megadose methylprednisolone (MDMP) support fairly closely our complete remission results, though theirs was a retrospective evaluation. In our prospective, comparative study, antiplatelet antibodies were also determined3. Their 80% complete remission rate (mistakenly written as 66% in the text) with MDMP administration was much better than other therapeutic approach...
متن کاملLow-dose vincristine in the treatment of corticosteroid-refractory idiopathic thrombocytopenic purpura (ITP) in non-splenectomized patients.
Eight non-splenectomized patients with corticosteroid-refractory idiopathic thrombocytopenic purpura (ITP) were treated with low-dose vincristine (1 mg/week up to a total dose of 4 mg). Complete remission was achieved in 2 cases and partial remission in 3. Bleeding stopped in one patient who failed to remit. No statistical relationship was found between the response to vincristine and the durat...
متن کاملIdiopathic thrombocytopenic purpura (ITP) in children.
Idiopathic thrombocytopenic purpura in children remits spontaneously in the majority of cases but most children require treatment. Between 1995 and 2005, 265 children (0-15 years old) have been consecutively observed and treated: 28 children with high doses of methylprednisolone (HDMP) (15 mg/kgx4 days), 63 with HDMP (7.5 mg/kgx4 days), 37 with HD dexamethasone (DXM) pulses, 29 with low doses o...
متن کاملPlatelet kinetic study in patients with idiopathic thrombocytopenic purpura (ITP) refractory or relapsing after corticosteroid treatment.
BACKGROUND A platelet kinetic study (PKS) is not indicated in the evaluation of adult patients with idiopathic thrombocytopenic purpura (ITP) at presentation. However, in ITP patients refractory to or relapsing after corticosteroid therapy, its appropriateness is considered uncertain. METHODS We prospectively performed a PKS with (111)In oxine-labeled autologous platelets in 93 consecutive ad...
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ژورنال
عنوان ژورنال: IOSR Journal of Environmental Science, Toxicology and Food Technology
سال: 2013
ISSN: 2319-2399,2319-2402
DOI: 10.9790/2402-0331527